Assymmetric Reduction of Aromatic Ketone in a Continuous Flow System

DOI: 10.1246/bcsj.59.3329

Source and publish data:

Bulletin of the Chemical Society of Japan p. 3329 - 3331 (1986)

Update date:2022-08-31

Topics:

Authors:

Itsuno, Shinichi

Ito, Koichi

Maruyama, Toshihiro

Kanda, Naoki

Hirao, Akira

Nakahama, Seiichi

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Article abstract of DOI:10.1246/bcsj.59.3329

When THF-borane (1/1) and aromatic ketone were supplied continuously to the column containing polymer-supported (S)-(-)-2-amino-3-(p-hydroxyphenyl)-1,1-diphenyl-1-propanol, the chiral product, secondary benzylic alcohol, could be obtained successfully (>9

Full text of DOI:10.1246/bcsj.59.3329

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