Bioorganic and Medicinal Chemistry Letters p. 189 - 194 (1998)
Update date:2022-08-02
Topics:
Ojima, Iwao
Bounaud, Pierre-Yves
Takeuchi, Craig
Pera, Paula
Bernacki, Ralph J.
New non-cytotoxic taxanes synthesized from 10-deacetylbaccatin III and special hydrophobic acylating agents show remarkable MDR reversal activity (≤99.8%) against drug-resistant human breast cancer cells when co-administered with paclitaxel or doxorubicin. This activity is ascribed to the highly efficient blocking of P-glycoprotein efflux by these new taxanes.
View MoreChongqing Rong&Quan Pharmaceutical Technology Co. , Ltd.
Contact:86-023-65268721
Address:No. 7, Manshanhong Village, Pingdingshan, Shapingba District, Chongqing Province, China
Jiangxi Dongxu Chemical Science & Technology Co.,Ltd
Contact:+86-791-86899381
Address:Nanchang, Jiangxi, China
HaiNan Periwinkle Pharmaceutical Co.,Ltd.
website:http://www.cchpharm.com/en/index.html
Contact:020-82208978
Address:Gongye road,Wuzhishan city,HaiNan province
Shandong Yaroma Perfumery Co., Ltd.
Contact:+86- 531- 88024598
Address:7-702 Caizhi Central, 59 Gong Ye South Road, Jinan City,250101, P. R. China
Sinoway International (Jiangsu) Co., Ltd.
Contact:+86-25-86630167
Address:17 Beijing Road (West), Nanjing, China
Doi:10.1016/j.tet.2021.132387
(2021)Doi:10.1039/c3ob42341g
(2014)Doi:10.1021/jo01267a010
(1968)Doi:10.1016/j.tet.2015.05.115
(2015)Doi:10.1021/jm00052a010
(1994)Doi:10.1039/d1ob00942g
(2021)