Solid-phase enzymatic synthesis of oligonucleotides.

DOI: 10.1021/ol990240n

Source and publish data:

Organic letters p. 1729 - 1731 (1999)

Update date:2022-08-30

Topics:

Authors:

Schmitz Schmitz

Reetz Reetz

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Article abstract of DOI:10.1021/ol990240n

[formula: see text] The controlled and selective synthesis of oligonucleotides on the solid phase is possible under mild aqueous conditions using the enzyme T4 RNA ligase, the resins being tentagel or kieselguhr/polydimethylacrylamide.

Full text of DOI:10.1021/ol990240n

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