Angewandte Chemie - International Edition in English p. 1211 - 1212 (1997)
Update date:2022-08-17
Topics:
Larsson
Persson
Backvall
A specifically designed acyl donor, an efficient enzyme, and a stable and reliable ruthenium catalyst are fundamental for the resolution of the racemic alcohols described here (see scheme on the right). For R1 = Ph and R2 = Me, 100% conversion into the corresponding acetate was achieved with greater than 99.5% cc.
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