Synthesis and antiproliferative activity of 17-[1′,2′,3′]-selenadiazolylpregnenolone compounds

Article abstract of DOI:10.1016/j.steroids.2018.10.004

Using pregnenolone as a starting material, some 3-substituted 17-[1′,2′,3′]-selenadiazolylpregnenolone derivatives were synthesized, and their structures were characterized by IR, NMR and HRMS. The in vitro antitumor activity of the compounds was assayed