Polyanion inhibitors of human immunodeficiency virus. Part IV. - Polymerized anionic surfactants : Influence of the density and distribution of anionic groups on the antiviral activity

Article abstract of DOI:10.1016/0960-894X(96)00042-X

The synthesis of a series of new polyanions, via γ-polymerization, of ω-unsaturated multi-charged anionic surfactants, has been realized. These polyanions were evaluated for their activity against HIV-1. All tested compounds proved active without presenting toxicity to the host cells (CEM-4 or MT-4).