Tetrahedron Letters p. 2685 - 2688 (1999)
Update date:2022-08-17
Topics:
Sammakia, Tarek
Jacobs, Jon S.
The use of picolinic acid and 6-methyl picolinic acid in the Mitsunobu reaction has been studied. These substrates are excellent partners in the Mitsunobu reaction, and offer the added advantage that the resulting esters can be cleaved under essentially neutral conditions using Cu(OAc)2 and methanol.
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