Synthetic Communications p. 3125 - 3134 (2010)
Update date:2022-08-29
Topics:
Zhang, Aiying
Yu, Mingfeng
Lan, Tian
Liu, Zenglu
Mao, Zhenmin
A simple and convenient route for synthesis of a series of 4-or 6-substituted indirubin derivatives by oxidation and subsequent condensation of indoxyl and isatin is described. Acidic reaction conditions are crucial to the condensation of 4-substituted derivatives, whereas for the condensation of 6-substituted derivatives, both acidic and basic conditions work well. Copyright Taylor & Francis Group, LLC.
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