Improved solid phase synthesis of C-terminal peptide aldehydes

DOI: 10.1016/0040-4039(95)01646-Y

Source and publish data:

Tetrahedron Letters p. 7871 - 7874 (1995)

Update date:2022-08-11

Topics:

Authors:

Fehrentz, Jean-Alain

Paris, Marielle

Heitz, Annie

Velek, Jiri

Liu, Chuan-Fa

et al. et al.

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Article abstract of DOI:10.1016/0040-4039(95)01646-Y

A new linker based on the Weinreb amide was developed in order to synthesize from peptidyl-resin the corresponding aldehydic peptides by reduction with LiAlH4.This new reaction was tested with N-protected amino-residues and with tripeptides to obtain the

Full text of DOI:10.1016/0040-4039(95)01646-Y

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