Synthesis of C5-substituted AE-bicyclic analogues of lycoctonine, inuline and methyllycaconitine

DOI: 10.1016/S0040-4039(97)10648-7

Source and publish data:

Tetrahedron Letters p. 889 - 892 (1998)

Update date:2022-08-11

Topics:

Authors:

Grangier, Geraldine

Trigg, William J.

Lewis, Terence

Rowan, Michael G.

Potter, Barry V. L.

Blagbrough, Ian S.

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Article abstract of DOI:10.1016/S0040-4039(97)10648-7

We have prepared C5-substituted AE-bicyclic analogues of norditerpenoid alkaloids lycoctonine, inuline and methyllycaconitine via an acetylide anion addition strategy. Using two acetylide anions, we have regioselectively linked two cyclic ketones to acetylene.

Full text of DOI:10.1016/S0040-4039(97)10648-7

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