Development and in Vitro and in Vivo evaluation of microspheres containing sodium N-[8-(2-hydroxybenzoyl)amino]caprylate for the oral delivery of berberine hydrochloride

Article abstract of DOI:10.3390/molecules25081957

Microspheres containing absorption enhancer (sodium N-[8-(2-hydroxybenzoyl) amino]caprylate, SNAC) were developed to enhance the oral bioavailability of berberine hydrochloride (BER) with poor intestinal membrane permeability. Microspheres were prepared a