AN APPROACH TO LIPOPHILIC NUCLEOTIDE POHPSPHATE ANALOGS.SYNTHESIS OF A LIPOPHILIC ISOSTERE OF ATP.

DOI: 10.1016/0040-4039(88)85241-9

Source and publish data:

Tetrahedron Letters p. 2615 - 2618 (1988)

Update date:2022-08-29

Topics:

Authors:

Otoski, Renee M.

Wilcox, Craig S.

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Article abstract of DOI:10.1016/0040-4039(88)85241-9

The tertiary structures of Mg²⁺ coplexes of ATP and ADP can be imitated by other, more lipophilic atomic arrangements.A design rationale is presented and a synthetic approach to such lipophilic ATP isosteres is described.

Full text of DOI:10.1016/0040-4039(88)85241-9

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