A stereospecific synthesis of vicinal amino alcohols by aminolysis of vinylepoxides

DOI: 10.1016/S0040-4039(97)00224-4

Source and publish data:

Tetrahedron Letters p. 2027 - 2030 (1997)

Update date:2022-08-29

Topics:

Authors:

Lindstroem, Ulf M.

Franckowiak, Remi

Pinault, Nathalie

Somfai, Peter

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Article abstract of DOI:10.1016/S0040-4039(97)00224-4

Several vinylepoxides have been prepared and subjected to a TsOH·H₂O-catalyzed aminolysis reaction to afford the corresponding amino alcohols in good yields. The nucleophilic addition is stereospecific and proceeds with high regioselectivity at

Full text of DOI:10.1016/S0040-4039(97)00224-4

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