N-3-oxoalkylamides and -thioamide in the synthesis of heterocyclic compounds. Part 1. Synthesis of 1,1-diethoxy-3-isothiocyanatobutane and reactions based on it

Article abstract of DOI:10.1007/BF02253030

The reaction of 3-isothiocyanatobutanal with ethanol in the presence of ethyl orthoformate produced 1,1-diethoxy-3-isothiocyanatobutane. The latter was used to devise methods of preparing 3-methylaminobutanal diethylacetal, N-(4-diethoxybutyl-2)thioamides