Journal of Pharmaceutical Sciences p. 1734 - 1737 (1984)
Update date:2022-08-17
Topics:
Sloan
Selk
Haslam
Caldwell
Shaffer
An N,N-dialkylhydroxylamine derivative of indomethacin has been synthesized. It has been shown to improve the delivery of indomethacin through mouse skin (compared to indomethacin itself) by a factor of two, to be more effective than indomethacin in inhibiting thermal inflammation (two to three times) in animal models, but to be only as effective as indomethacin in inhibiting UV-B radiation erythema in human volunteers.
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Doi:10.1055/s-0030-1260788
(2011)Doi:10.1002/cjoc.201500046
(2015)Doi:10.1002/ardp.19773101111
(1977)Doi:10.1007/s11164-014-1690-x
(2015)Doi:10.1007/s11172-005-0365-6
(2005)Doi:10.1007/s10895-021-02771-8
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