
Journal of the Chemical Society. Chemical communications p. 774 - 775 (1981)
Update date:2022-08-17
Topics:
Barton, Derek H. R.
Motherwell, William B.
Zard, Samir Z.
Steroidal 17-ketones react smoothly with diethyl α-isocyanoethyl phosphonate to give, after suitable oxidative and hydrolytic reactions, the dihydroxy-acetone side-chain of corticosteroids in high yield.
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