Helvetica Chimica Acta p. 172 - 179 (1989)
Update date:2022-08-03
Topics:
Hugener, Martin
Heimgartner, Heinz
The reaction of 3-(dimethylamino)-2H-azirines 1 and 2-(trifluoromethyl)-1,3-oxazol-5(2H)-ones 5 in MeCN or THF at 50-80 deg leads to 5-(dimethylamino)-3,6-dihydropyrazin-2(1H)-ones 6 (Scheme 3).Reaction mechanisms for the formation of 6 are discussed: eit
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Doi:10.1021/ja036288k
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(1963)
