Palladium-Catalyzed Cyclization of Benzyl Halides and Related Electrophiles Containing Alkenes and Alkynes as a Novel Route to Carbocycles

Article abstract of DOI:10.1021/jo00272a006

Treatment of benzyl halides and related electrophiles containing alkene and alkyne groups with a catalytic amount of Pd complexes, such as Pd(PPh3)4, provides the corresponding cyclization products containing five- through seven-membered rings often with retention of the alkene regiochemistry.