Enantioselective synthesis of juvenile hormone III in three steps from methyl farnesoate

Article abstract of DOI:10.1055/s-1993-25939

The asymmetric dihydroxylation of methyl farnesoate resulted in regioselective dihydroxylation of the 10,11 olefin to give the (10S) and (10R)-(2E,6E)-10,11-dihydroxy-3,7,11-trimethyl-2,6-dodecadienoates in high ee. These diols were converted to juvenile hormone III and its enantiomer.