ASYMMETRIC SYNTHESIS OF HETEROORGANIC ANALOGS OF NATURAL PRODUCTS. 6. (S)-α-AMINO-ω-PHOSPHONOCARBOXYLIC ACIDS

Article abstract of DOI:10.1007/BF00869521

Alkylation, by ω-haloalkylphosphonates, of the Ni(II) complex of the Schiff base formed from glycine and (S)-2-N-(N¹-benzylproplyl)-o-aminobenzophenone has been used for the asymmetric synthesis of (S)-2-amino-4-phosphonobutyric and (S)-2-amino-5-phosphonovaleric acids. Keywords: asymmetric synthesis; (S)-α-amino-ω-phosphonocarboxylic acids.