Enantioselective Oxidation of Thioethers: an Easy Route to Enantiopure C2 Symmetrical bis-Methylsulfinylbenzenes

Article abstract of DOI:10.1016/S0040-4039(00)60497-5

The direct oxidation of bis-methylthioethers 1 by t-butyl hydroperoxide, titanium tetra-isopropylate and (+)-diethyl tartrate, affords the almost enantiomerically pure dl bis-methylsulfinylbenzenes 2 (e.e. >/= 99percent) in a process which is also charact