Tetrahedron Letters p. 6809 - 6812 (1999)
Update date:2022-08-12
Topics:
Komine, Nobuyuki
Wang, Lan-Fang
Tomooka, Katsuhiko
Nakai, Takeshi
Treatment of benzyl methyl ether with a t-BuLi/chiral bis(oxazoline) complex followed by carboxylation is shown to afford α-methoxy phenylacetic acid in high % ee (up to 95%). The asymmetric induction was proved to occur at the post-lithiation step.
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