New bicyclic antidepressant agent. Synthesis and activity of napactadine and related compounds

DOI: 10.1021/jm00149a031

Source and publish data:

Journal of Medicinal Chemistry p. 1721 - 1727 (1985)

Update date:2022-08-11

Topics:

Authors:

McCarthy

Wright Wright

Schuster

Abdallah

Shea Shea

Eyster Eyster

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Article abstract of DOI:10.1021/jm00149a031

A number of N,N'-dialkylarylamidines were synthesized and evaluated for antidepressan activity. Several of these compounds were synthesized from the corresponding nitriles by a new method. Slight structural modification in the series caused a marked chang

Full text of DOI:10.1021/jm00149a031

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