Highly oxygenated flavonoids from Murraya paniculata

Article abstract of DOI:10.1016/0031-9422(96)00058-1

Eight highly oxygenated flavones, including one new compound, were isolated from the leaves of an Indonesian medicinal plant, Murraya paniculata. Seven of them were identified as 5-hydroxy-6,7,8,3',4',5'- hexamethoxyflavone (gardenin A), 5,3'-dihydroxy-6,7,8,4',5'- pentamethoxyflavone (gardenin C), 6,7,8,4'-tetra-methoxy-5,3',5'- trihydroxyflavone (gardenin E), 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone (5- O-desmethylnobiletin), 6,7,8,3',4',5'-hexamethoxyflavone, 5-hydroxy- 6,7,3',4',5'-pentamethoxyflavone (umhengerin), 5,3'-dihydroxy-6,7,4',5'- tetramethoxyflavone either by direct comparison with authentic samples or by comparing their melting points and spectroscopic data with those reported in the literature. The new compound was elucidated as 5,3',5'-trihydroxy- 6,7,4'-trimethoxyflavone on the basis of chemical and spectroscopic studies.