Bulletin of the Chemical Society of Japan p. 3483 - 3485 (1983)
Update date:2022-08-12
Topics:
Shimidzu, Takeo
Yamana, Kazushige
Kanda, Naoya
Kitagawa, Susumu
Tri(1-imidazolyl)phosphine (1) gave the cyclic phosphite quantitatively in the reactions with the diols possessing favorably placed hydroxyl groups in which the distance between the two oxygen atoms is 2.7-3.0 Angstroem.The both five- and six-membered cyclic phosphites were obtained quantitatively from the reactions of the diols possessing flexible chains with 1.The course of the selective formation of ribonucleoside 2',3'-cyclic 1-imidazolylphosphonite was interpretated by the higher reactivity of 1 toward the 2'- or 3'-hydroxyl group than toward the 5'-hydroxyl group of ribonucleoside.
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