Phosphorus, Sulfur and Silicon and the Related Elements p. 1735 - 1738 (2002)
Update date:2022-08-17
Topics:
De Rouveze, Marie-Caroline Aoust
Gilard, Veronique
Martino, Robert
Malet-Martino, Myriam
Niemeyer, Ulf
31P NMR was used to demonstrate that glufosfamide is hydrolyzed into isophosphoramide mustard (IPM) with a half-life of about 25 h at 37°C and pH 7.4 in buffer as well as in human plasma. Through a cascade of reactions, IPM gives rise to three
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