FURTHER INSIGHT INTO LOWER ORDER CUPRATE CHEMISTRY; ON THE USE OF CuBr*Me2S VS CuI EN ROUTE TO R2CuLi

Article abstract of DOI:10.1016/S0040-4039(00)94250-3

Both (1)H and (7)Li NMR experiments show that 2MeLi + either CuBr*Me2S or CuI in THF afford the same species, Me2CuLi (+ LiX).However, use of the former source of Cu(I), depending upon its purity and especially handling, can lead to significantly decreased chemical yields.The reasons behind these observations and the implications for cuprate couplings are discussed.