Molecules (2019)
Update date:2022-08-29
Topics:
Ternon, Eva
Wang, Yanfei
Coyne, Kathryn J.
Due to increasing evidence of key chemically mediated interactions in marine ecosystems, a real interest in the characterization of the metabolites involved in such intra and interspecific interactions has emerged over the past decade. Nevertheless, only a small number of studies have succeeded in identifying the chemical structure of compounds of interest. One reason for this low success rate is the small size and extremely polar features of many of these chemical compounds. Indeed, a major challenge in the search for active metabolites is the extraction of small polar compounds from seawater. Yet, a full characterization of those metabolites is necessary to understand the interactions they mediate. In this context, the study presented here aims to provide a methodology for the characterization of highly polar, low molecular weight compounds in a seawater matrix that could provide guidance for marine ecologists in their efforts to identify active metabolites. This methodology was applied to the investigation of the chemical structure of an algicidal compound secreted by the bacteria Shewanella sp. IRI-160 that was previously shown to induce programmed cell death in dinoflagellates. The results suggest that the algicidal effects may be attributed to synergistic effects of small amines (ammonium, 4-aminobutanal) derived from the catabolization of putrescine produced in large quantities (0.05-6.5 fmol/cell) by Shewanella sp. IRI- 160.
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Doi:10.1021/j100289a041
(1987)Doi:10.1016/S0040-4039(03)01800-8
(2003)Doi:10.1055/s-0037-1611362
(2019)Doi:10.1007/BF00763383
(1988)Doi:10.1021/acsmedchemlett.0c00375
(2020)Doi:10.1002/jhet.3185
(2018)