Heteroatom Chemistry p. 542 - 545 (2003)
Update date:2022-08-16
Topics:
Wang, Qingmin
Liu, Gang
Shao, Ruilian
Huang, Runqiu
Reaction of 6-phenyl-4-thioxo-1,3,5-triazine-2-one with alkyl halide in the presence of 1 equiv. of sodium hydroxide resulted in 4-alkylthio-6-phenyl-1,3,5-triazine-2-one in good yield, whereas the above reaction provided 2-alkoxyl-4-alkylthio-6-phenyl-1,3,5-triazine in the presence of 2 equiv. of sodium hydroxide. 6-Phenyl-4-thioxo-1,3,5-triazine-2-one was oxidized with hydrogen peroxide to give 6-phenyl-1,3,5-triazine-2,4-dione. Further treatment with ethyl bromoacetate or (substituted) benzyl bromides yielded 2,4-dialkoxy-6-phenyl-1,3,5-triazines. At the same time, a small amount of 2-dimethylamino-4-alkoxy-6-phenyl-1,3,5-triazine were isolated. Preliminary bioassays indicate that the title compounds possess good activities against tobacco mosaic virus.
View MoreNanjing Ruizhi Industry & Technologh Co.,Ltd.
Contact:+86-25-86808110
Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
Chengdu Green Young Biopharmaceutical INC
Contact:+86-28-85337952
Address:1-B-26,Tianhe Industry Park, No.1480 of Tianfu Road,Chengdu,P.R.China,610000
Hangzhou Deli Chemical Co.,Ltd.
website:http://www.dlchemical.com
Contact:86 571 28006267
Address:Tangxi Industrial Area, Yuhang District, Hangzhou
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.
Contact:15857995878 0579-82207761
Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Shanghai Yurui Biotechnology(Anyang) Pharmaceutical Co., Ltd
Contact:+86-0372-3662335 +86-0372-3661988
Address:hanling industrial park anyang
Doi:10.1016/S0957-4166(00)00190-7
(2000)Doi:10.1016/0040-4039(95)01673-6
(1995)Doi:10.1016/S0040-4039(00)97372-6
(1990)Doi:10.1021/ja00853a027
(1975)Doi:10.3762/bjoc.14.193
(2018)Doi:10.1016/j.ejmech.2021.113376
(2021)