Halocarbon Chemistry. 3. Ortho Metallation-Induced Cyclization of Acetylenes: One-Flask Synthesis of 2,3-Disubstituted Benzofurans, Thianaphthenes, and Indoles

DOI: 10.1021/jo00375a063

Source and publish data:

Journal of Organic Chemistry p. 5040 - 5041 (1986)

Update date:2022-08-29

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Authors:

Johnson, Francis

Subramanian, Raghupathi

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Article abstract of DOI:10.1021/jo00375a063

A new base-induced cyclization is described which involves the direct one-pot conversion of trifluoroethyl phenyl ethers, thioethers, and amines, in the presence of 4 equiv of alkyl- or aryllithium reagents, to 2,3-disubstituted benzofurans, thianaphthene

Full text of DOI:10.1021/jo00375a063

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