Tetrahedron Letters p. 4103 - 4104 (1983)
Update date:2022-08-17
Topics:
Tanaka, T.
Toru, T.
Okamura, N.
Hazato, A.
Sugiura, K.
et al.
(-)-Prostaglandin E1 has been prepared from (R)-4-t-butyldimethylsiloxy-2-cyclopentenone by using as a key operation the tandem organocopper conjugate addition/nitroolefin Michael trapping of the resulting enolate intermediate.
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