
Journal of Organic Chemistry p. 7627 - 7629 (1993)
Update date:2022-08-28
Topics:
Willoughby, Christopher A.
Buchwald, Stephen L.
The asymmetric hydrogenation of cyclic ketimines with a chiral titanocene catalyst affords amines with excellent enantioselectivity under a variety of conditions.The reaction is general for cyclic imines of ring size 5-7 and exhibits a high degree of functional group compatibility.
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