QUATERNIZATION OF TETRAZOLES UNDER HIGH PRESSURE AND ESTABLISHMENT OF THE STRUCTURES OF QUATERNARY TETRAZOLIUM SALTS BY 13C NMR SPECTROSCOPY

Article abstract of DOI:10.1007/BF00506596

The quaternization of 1- and 2-acetonyl-5-R-tetrazoles, as well as dimethyltetrazole, was accomplished under high pressure conditions (5000-14,000 kgf/cm²) by means of bromoacetone and methyl iodide and at atmospheric pressure and room temperature under the influence of methyl fluorosulfate.The structure of the salts were ascertained by 13C NMR spectroscopy, and the principles of the change in the chemical shifts and the spin-spin coupling constants during quaternization and protonation of the tetrazoles were studied.