Synthesis of 4-Chloro-1,2,3-tiazole Derivatives by Diazotization of 6-Substituted 5-Amino-4-chloropyrimidines

Article abstract of DOI:10.1007/BF00505769

It is shown that 4-cyano- and 4-carbalkoxy-5-chloro-1,2,3-triazoles, respectively, are formed in the diazotization of 4,6-dichloro- and 4-chloro-6-alkoxy-5-aminopyrimidines.It was observed that a methyl group in the 2 position of the starting pyrimidine derivative does not affect the structures of the reaction products under the described conditions.