Chemistry of Heterocyclic Compounds p. 279 - 282 (1985)
Update date:2022-08-16
Topics:
Petrulyanis, L. N.
Veinberg, G. A.
Kononov, L. I.
Dreibante, I. I.
Lukevits, E. Ya.
New N-acylureido and N-acylthioureido derivatives of β-lactam antibiotics were obtained by the reaction of 6-ureido and 6-thioureidopenicillanic and 7-thioreidodeacetoxycephalosporanic acids with acyl halides of carboxylic acids and benzoyl isocyanate. 6-Carbamoylhydroxypenicillanic acid, 6-thiocarbamoylhydroxypenicillanic acid, and its trichloroethyl ester were obtained by treatment of 6-α-hydroxypenicillanic acid and its trichloroethyl ester with isocyanatosilanes with subsequent hydrolysis of the N-silylcyanato groups.
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Doi:10.1021/jo010757o
(2002)Doi:10.1021/om0202470
(2002)Doi:10.1016/S0040-4039(02)00242-3
(2002)Doi:10.1021/jo020089m
(2002)Doi:10.1592/phco.22.8.551.33205
(1932)Doi:10.1039/b107113k
(2002)
