The first synthesis of a 2',3'-methano carbocyclic nucleoside

DOI: 10.1016/S0040-4039(99)01910-3

Source and publish data:

Tetrahedron Letters p. 9069 - 9072 (1999)

Update date:2022-08-12

Topics:

Authors:

Katagiri, Nobuya

Yamatoya, Yoshitsugu

Ishikura, Minoru

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Article abstract of DOI:10.1016/S0040-4039(99)01910-3

A 2',3'-methano carbocyclic nucleoside, 9-(c-4-hydroxymethylbicyclo[3.1.0]hex-r-2-yl)-9H-adenine, has been efficiently synthesized from 2-azabicyclo[2.2.1]hex-5-en-3-one(ABH) in six steps involving 1,3-dipolar cycloaddition, photolysis, and adenine ring c

Full text of DOI:10.1016/S0040-4039(99)01910-3

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Product name:Bicyclo[3.1.0]hexane-2-methanol, 4-amino-, (1R,2R,4S,5S)-rel- (9CI)

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