(S)-(-)-2-tert-butyl-3-methylene-oxirane: Synthesis and hydroboration of a chiral allene oxide

Article abstract of DOI:10.1016/0957-4166(94)80126-6

The chiral allene oxide, (S)-(-)-2-tert-butyl-3-methylene-oxiran 12 ((S)-(-)-1-tert-butylallene oxide) was prepared in a moderate yield and in high enantiomeric excess by a three-step conversion starting from 4,4-dimethyl-2-pentyn-1-ol 6. The procedure wa