Tetrahedron Letters p. 5335 - 5338 (1992)
Update date:2022-08-25
Topics:
Jaehne, Gerhard
Mueller, Armin
Kroha, Herbert
Roesner, Manfred
Holzhaeuser, Otto
Meichsner, Christoph
Helsberg, Matthias
Winkler, Irvin
Riess, Guenther
A versatile and high-yielding synthesis of racemic carbocyclic phosphonate nucleosides of adenine, hypoxanthine, guanine, cytosine, uracil, and thymine has been developed. These newly prepared compounds are isosteric (and isoelectronic) with (carbo)cyclic 2′,3′-dideoxy- and 2′,3′-dideoxy-2′,3′-didehydronucleoside monophosphates.
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