Journal of the Chemical Society. Perkin transactions II p. 399 - 402 (1988)
Update date:2022-08-17
Topics:
Hibbert, Frank
Sellens, Rowena J.
The rate coefficient for hydrolysis of 1-acetoxy-8-acetylaminonaphthalene to 1-hydroxy-8-acetylaminonaphthalene in aqueous sodium hydroxide shows a curved dependence on hydroxide ion concentration.Similar results are observed for the 3,6-disulphonate and five substituted 1-benzoyloxy-8-benzoylamino-3,6-disulphonates.In the proposed mechanism the ester group undergoes intermolecular attack by hydroxide ion in competition with intramolecular attack by the amide group.The latter generates an imide intermediate in equilibrium with the ester via a rapid acyl transfer, and since the imide is hydrolysed slowly to product its formation inhibits the ester hydrolysis.
View MoreYancheng Creator Chemical Co., Ltd
Contact:0086-515-88710008 88710068 88710858 88710868
Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Jinan Yijialian Economic and Trade Development Co., Ltd.
Contact:+86 0531-66729596
Address:jinan
Jinan Jinguilin Chemical Co.,Ltd
Contact:+86-531-81188412
Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD
Contact:+86-531-55696072
Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Contact:86-21-50966856
Address:Building 5,300 Chuanzhan Road,Pudong New District,Shanghai
Doi:10.1021/ja00791a084
(1973)Doi:10.1002/anie.201804094
(2018)Doi:10.1039/c7ob00178a
(2017)Doi:10.1039/jr9360001273
(1936)Doi:10.1016/0031-9422(89)80019-6
(1989)Doi:10.1055/s-1977-24470
(1977)
