Transition metal promoted synthesis of N,N-dimethyl tertiary amides from 1,3-dienes

Article abstract of DOI:10.1016/0040-4039(95)02076-4

A new procedure for a direct conversion of 1,3-dienes into N,N-dimethyl unsaturated tertiary amides is reported. η³-Allyltitanium(III) complexes generated in situ from various dienes reacted regiospecifically with dimethylcarbamoyl chloride to afford products in good to moderate yields. Acyclic, cyclic, incoporated into the polyene systems, and even sterically demanding dienes can be employed.