Journal of Heterocyclic Chemistry p. 883 - 884 (1989)
Update date:2022-08-11
Topics:
Botta
Artico
Massa
Gambacorta
The synthesis of 2,4-diamino-6-(3,4,5-trimethoxybenzyl)pyrimidine (isotrimethoprim) has been accomplished starting from 2-(O-methyl)-6-(3,4,5-trimethoxybenzyl)uracil by standard procedures. The benzyluracil derivative has been obtained by reacting O-methy
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Doi:10.1039/jr9610000341
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