Selective N-Alkylation of Imidazole with Alcohols over Calcined Layered Double Hydroxides

Article abstract of DOI:10.1246/bcsj.70.2829

Vapor-phase N-alkylation syntheses of imidazole were carried out with MeOH and EtOH over a series of calcined Mg^II-Al^III layered double hydroxides (LDHs) selectively produced in high yields of N-methyl (70%) and N-ethyl (63%) imidazoles only on the 3 : 1 atomic ratio of Mg^II-Al^III calcined LDH. Attempts on C-alkylation and dialkylation reactions over the same catalysts proved to be unsuccessful.