Friedlaender reaction of 3-acetyltropolones: Synthesis of naphthyridinyl- and allied heterocyclic-substituted tropolones

Article abstract of DOI:10.1002/jhet.5570330230

Five 3-acetyltropolones reacted with 2-amino-3-pyridinecarbaldehyde to afford the corresponding 3-(1,8-naphtliyridin-2-yl)tropoIones in excellent yields. In a similar manner, 1,6-naphthyridin-2-yl-, 1,7-naphthyridin-2-yl-, 6-pyrido[2,3-&]pyrazinyl-, and 1