Tetrahedron Letters p. 4433 - 4436 (1997)
Update date:2022-08-11
Topics:
Shindo, Mitsuru
A new method for ynolate synthesis via the cleavage of ester dianions has been developed. The key intermediates, ester dianions, generated from α-bromocarboxylic acid ester enolates via lithium-halogen exchange turned out to be so labile that they were cleaved rapidly to give ynolates.
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