Carbohydrate Research p. 85 - 94 (1983)
Update date:2022-08-11
Topics:
Fedoronko, Michal
Petrusova, Maria
Tvaroska, Igor
2-Methoxypropenal in acid media undergoes general acid-catalyzed hydrolysis with formation of 2-oxopropanal.The kinetics of this reaction were studied, the rate constants established, and a reaction mechanism is suggested.Hydrolysis of 2-methoxypropenal is governed by a mechanism of the vinyl ether type, and the presence of the aldehyde group causes a decrease in the reaction rate.The analogy of the acid-catalyzed hydrolysis of 2-methoxypropenal to that of a vinyl ether was shown by the solvent isotope-effect, kD/kH=0.41, and the value of the Broensted exponent, α=0.60.The activation parameters found and quantum-chemical calculations of charge distribution in 2-methoxypropenal and other model compounds were also utilized to explain the mechanism of the acid-catalyzed hydrolysis of the title compound.
View MoreShanghai Sungo Technology Chemical Co., Ltd
Contact:0086-21-51385579
Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Shanghai Yingrui Biopharma Co., Ltd
Contact:021-3358 8661*8003
Address:shanghai
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Suqian Ruixing Chemical Co., Ltd.
Contact:+86-527-80805666(总机);84836008(销售)
Address:3 Jingsilu, Zone north, Hubin Xincheng Development Park, Suqian, China
Chengdu D-Innovation Pharmaceutical Co., Ltd
Contact:86-28-85105536
Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Doi:10.1016/j.bmcl.2014.04.099
(2014)Doi:10.1016/S0022-328X(00)81122-5
(1969)Doi:10.1021/jo0624187
(2007)Doi:10.1021/acs.orglett.7b03994
(2018)Doi:10.1007/s11172-006-0115-4
(2005)Doi:10.1002/anie.202105830
(2021)