Sesquiterpenoid Constituents of Eight Porostome Nudibranchs

Article abstract of DOI:10.1021/jo00159a014

Sesquiterpenes of the drimane series were isolated from eight porostome nudibranchs.A mixture of polygodial (1) and olepupuane (3), a new sesquiterpene diacetate, was obtained from Dendrodoris nigra, Dendrodoris tuberculosa, and Dendrodoris krebsii.Olepupuane (3) and the sesquiterpene esters 5 were found in Doriopsilla albopunctata, Doriopsilla janaina, and an undescribed yellow porostome, although one collection of Doriopsilla albopunctata contained only olepupuane (3) while a second collection contained a related methoxy acetal 4.Two undescribed porostomes contained only the sesquiterpene esters 5 found previously in Dendrodoris limbata.The structures of olepupuane (3) and the methoxy acetal 4 are based on interpretation of spectral data.