Journal of the Chemical Society. Chemical communications p. 1335 - 1336 (1987)
Update date:2022-08-11
Topics:
Kunugi, S.
Tanabe, K.
Fukuda, M.
Makimoto, S.
Taniguchi, Y.
Peptide formation from an N-acyl amino acid ester and an amino acid amide using carboxypeptidase Y as a catalyst was shown to be considerably influenced by applying high pressure; at 150 MPa the peptide yield was almost five-fold higher than that at 0.1 MPa when PheNH2 was used as the nucleophile.
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