Journal of Medicinal Chemistry p. 3037 - 3045 (2007)
Update date:2022-08-17
Topics:
Prekupec, Svjetlana
Makuc, Damjan
Plavec, Janez
?uman, Lidija
Kralj, Marijeta
Paveli?, Kre?imir
Balzarini, Jan
De Clercq, Erik
Mintas, Mladen
Rai?-Mali?, Silvana
The synthetic route for introduction of a fluoroalkyl (7-12,14), fluoroalkenyl (15 and 16), fluorophenylalkyl (17, 19, 20, and 22), and fluorophenylalkenyl (18, 21) side chain at C-6 of the pyrimidine involved the lithiation of the pyrimidine derivatives
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