Rx:RN
Holistic Management
of Thyroid Dysfunction
The Nurse’s Role
the thyroid hormones, thyroxine (T ),
4
ation exposure. Thyroid disorders may
also be caused by autoimmune condi-
tions, such as Graves’ disease and
Samten Williams, B.S.N., R.N.
the stored form of the hormone, and tri-
iodothyronine, (T ) the active form of
3 ,
the hormone. The subscript numbers
relate to the number of iodine molecules
Hashimoto’s thyroiditis. Family history
12
may be a factor
ypothyroidism, the most com-
mon form of thyroid disorder,
and some researchers
7–9
within each molecule of the hormone.
speculate that exposure to toxic sub-
stances in the environment may trigger an
autoimmune response.
affects one woman of ten over
The thyroid gland is self-regulated by a
complex system of negative feedback
loops that start with the secretion of thy-
rotropin-releasing hormone (TRH) in the
hypothalamus. Once released, TRH com-
municates with the pituitary gland to
release thyroid-stimulating hormone
(TSH). It is this hormone, TSH, that com-
municates with the thyroid gland to pro-
duce T . The hormone T is then produced
H
1,2
the age of 65.
This group of elders is
not the only cohort that is affected by
thyroid conditions. The 1999 United
States Census estimate, which is the lat-
est information available to date, indi-
cates that 5.40 million American men
and women in the general population
The Challenge of Diagnosing
Thyroid Dysfunction
Confirming a diagnosis of hypothy-
roidism is a challenging process because
the standard test used to check thyroid
function, the TSH test, is not sensitive
enough to diagnose many borderline suf-
ferers.
Denis St. J. O’Reilly, a consultant clini-
cal biochemist in the department of clini-
cal biochemistry and clinic for thyroid
diseases, at the Royal Infirmary, Glasgow,
Scotland, has 20 years of research and
clinical experience working with patients
who have thyroid disorders. Addressing
the chaos in the medical community
regarding the diagnosis of hypothy-
roidism, Dr. St. J. O’Reilly calls for a
reassessment of thyroid-function tests.
This reassessment is needed for the fol-
lowing reasons:
3
are treated for thyroid dysfunction. In
addition, an estimated 13–20 million
Americans may not know that they have
4
3
from T
by the removal of an iodine
4
4–6
8,9
thyroid conditions.
molecule. These thyroid hormones are
responsible for cellular metabolism
throughout the entire body.
People who suffer from thyroid dys-
function need health care providers who
have a sophisticated understanding of
the testing, diagnosis, and treatment of
thyroid disorders. Conventionally, via
assessment, education, and communica-
tion, nursing has served as a bridge
between physicians and patients. This
nursing role is crucial now; it is the front
line of defense against a rise in thyroid
dysfunction in the United States.
Common thyroid disorders include
hyperthyroidism and hypothyroidism.
Caused by an overproduction of thyroid
hormones, hyperthyroidism causes over-
activity of body metabolism. Signs of an
overac tive thyroid may include an
enlarged thyroid gland, generalized ner-
vousness, weak muscles, weight loss,
moist skin, hair loss, palpitations, heat
intolerance, dyspnea, increased gastroin-
10
testional motility, insomnia, and fatigue.
The Thyroid in
Health and Dysfunction
The most prevalent form of thyroid
dysfunction, hypothyroidism, results
from an inadequate production of thy-
roid hormone. Symptoms of an underac-
tive thyroid may include puffiness in the
hands and face, weight gain, a hoarse
voice, dry skin, chronic constipation,
depression, intolerance to cold, memory
loss, muscle aches, bradycardia, and gen-
(1) Changes in thyroxine and triiodothy-
ronine levels during periods of sys-
temic illness are not well-understood.
(2) False-positive and false-negative
results can occur and should be consid-
ered when interpreting TSH levels.
The thyroid gland is the only tissue in
the body that can absorb iodine, an ele-
ment that is vital to hormonal chain
reactions. Absorbed through a normal
component of many foods, especially
sea vegetables, iodized salt, thyroid
medications, and supplements, iodine is
combined with an amino acid, tyrosine,
to form the basic building block that will
become the thyroid hormones. This ele-
ment/protein combination converts into
(3) The secretion of TSH, or lack thereof,
is influenced by many factors other
than negative feedback inhibition by
11
12
eralized fatigue.
thyroxine or triiodothyronine.
Thyroid conditions may also occur in
pregnant women or in newborns, or as a
result of cancer, or as a side-effect of radi-
Jacob Teitelbaum, M.D., director of the
Annapolis Research Center for Effective
Fibromyalgia Syndrome/Chronic Fatigue
384