TOWARDS A SYNTHESIS OF (+/-)MODHEPHENE VIA CASCADE REARRANGEMENT: SYNTHESIS AND REARRANGEMENT OF DISPIROUNDECANES TO PROPELLANES

Article abstract of DOI:10.1016/S0040-4039(00)80271-3

The dispiro<3.0.4.2>undecanes 2 and 6 undergo cascade rearrangements yielding the <3.3.3>propellanes 3 and 7, respectively.The rearrangement of 6 proceeds regiospecifically and renders 9 a promising candidate for a direct conversion to (+/-)modhephene 10.